Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity associated with bortezomib, a proteasome inhibitor Utilized in the treatment method of various myeloma. Its synthesis or review is essential for ensuring the purity and protection from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate most cancers by inhibiting androgen generation.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound within the synthesis of imatinib, a drug that targets specific varieties of cancer, such as Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats several cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are generally intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is essential for optimizing the production method and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is applied to treat breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the treatment method of breast most cancers. Numerous intermediates help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Utilized in the synthesis of paclitaxel, CAS NO. 848133-35-7 a chemotherapy drug effective in treating cancers for example ovarian, breast, and tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate lung cancer.
3. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the treatment of colorectal most cancers and little cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have many applications, which includes antiviral Houses.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type 2 diabetes that inhibits the enzyme DPP-four to control blood sugar ranges.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved in the synthesis of various gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilised to control variety 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).